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These findings were supported by another study that also administered 40 IU IN-OXT or placebo to male SZ patients and age-matched healthy controls to assess IN-OXT effects on autonomic (ability to interpret/understand emotional cues) versus controlled (ability to comprehend indirectly expressed emotions, thoughts, and intentions through complex deliberations) social cognition
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Likewise, the mRNA of inflammatory mediators (iNOS, IL-6, IFNγ and TNF-α) are inhibited, with increased expression of HSP 70 and 90, and antioxidant proteins, such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2 and GST-pi [19]